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Publications

Creaflow figure Selective and scalable oxygenation of heteroatoms using the elements of nature air water and light Beilstein Journal of Organic Chemistry

19 augustus 2023

Scientific publication: Selective and scalable oxygenation of heteroatoms using the elements of nature: air, water, and light

The study presents a selective and scalable oxygenation of heteroatoms using only air, water, and light. The approach is catalyst free, delivers high conversions with excellent selectivity, and works in batch as well as in flow. The…

Creaflow-Photoredox Csp3 Csp2 Reductive Cross Coup-ChemCatChemlings of Cereblon Ligands for PROTAC Linker Exploration in Batch and Flow-ChemCatChem

12 oktober 2023

Scientific publication: Photoredox C(sp3)-C(sp2) Reductive Cross-Couplings of Cereblon Ligands for PROTAC Linker Exploration in Batch and Flow

The study reports a visible light driven reductive cross-coupling that forges C(sp3)-C(sp2) bonds from cereblon based substrates and aryl partners. The authors outline reaction conditions that are broadly applicable, enabling late stage…

Creaflow figure An electrochemical oscillatory flow reactor with pillar array electrodes improving mass transfer in electrosynthesis Science Direct 2x

20 december 2022

Scientific publication: An electrochemical oscillatory flow reactor with pillar array electrodes improving mass transfer in electrosynthesis

The study introduces an electrochemical oscillatory flow reactor that applies a controlled oscillatory flow regime over conductive pillar-array electrodes. These pillars function as both electroactive interface and turbulence promoters,…

Rsz toc graphic revised 1v1

04 juni 2020

Scientific publication: Ir/Ni Photoredox Dual Catalysis with Heterogeneous Base Enabled by an Oscillatory Plug Flow Photoreactor

Continuous flow reactor technology has a proven track record in enabling photochemical transformations. However, transfer of a photochemical batch process to a flow protocol often remains elusive, especially when solid reagents or…

Rsz optimization of a decatungstate catalyzed csp3 h alkylation using a continuous oscillatory millistructured photoreactorv1 v1

09 juli 2020

Scientific publication: Optimization of a Decatungstate-Catalyzed C(Sp 3 )–H Alkylation Using a Continuous Oscillatory Millistructured Photoreactor

Tetrabutylammonium decatungstate (TBADT) has emerged as an efficient and versatile photocatalyst for hydrogen atom transfer (HAT) processes that enables the cleavage of both activated and unactivated aliphatic C–H bonds. 

Ontinuous flow processing of bismuth photocatalyzed atom transfer radical addition reactions using an oscillatory flow reactor v1 0

26 november 2020

Scientific publication: Continuous Flow Processing of Bismuth-Photocatalyzed Atom Transfer Radical Addition Reactions Using an Oscillatory Flow Reactor

Metal oxides represent an abundant and non-toxic class of photocatalysts for organic transformations. However, their use in larger scale processes is complicated by…

Rsz an oscillatory plug flow photoreactor facilitates semi heterogeneous dual nickel carbon nitride photocatalytic c n couplingsv1 3

14 februari 2020

Scientific publication: An Oscillatory Plug Flow Photoreactor Facilitates Semi-Heterogeneous Dual Nickel/Carbon Nitride Photocatalytic C–N Couplings

Carbon nitride materials have emerged as an efficient and sustainable class of heterogeneous photocatalysts, particularly when paired with nickel in dual catalytic cross-coupling reactions.

Photochemical Deracemization of a Medicinally Relevant Benzopyran using an Oscillatory Flow Reactor

08 juli 2021

Scientific publication: Photochemical Deracemization of a Medicinally-Relevant Benzopyran using an Oscillatory Flow Reactor

Photo-transformation: Unlike classical enantiomeric resolution methods, crystallization-induced diastereomer transformations (CIDTs) allow full conversion to the desired enantiomer.