News

13/04/2020 - 12:15

In their latest Organic Process Research & Development article, Ecosynth reports the application of the HANU™ reactor to enable a heterogeneous MacMillan-type C(sp2)–C(sp3) cross-electrophile coupling. Combination of an oscillatory flow regime with static mixing elements imparts exquisite control over the mixing intensity and residence time distribution, pinpointing a mindset shift concerning slurry handling in continuous flow reactors. The C(sp2)–C(sp3) cross-electrophile coupling was successfully transferred from batch to flow, resulting in an intensified slurry process with significantly reduced reaction time and increased productivity.

17/11/2018 - 11:22

Creaflow has successfully installed a pilot-scale version of the HANU-reactor at the premises of Ajinomoto Bio-Pharma Services in Wetteren, Belgium. This unit enables the scale-up of (photo)chemical processes that were developed and optimized in the lab HANU-reactor. Full implementation of the pilot reactor in a GMP environment is foreseen in early 2019.

03/10/2018 - 12:25

Creaflow has launched an upgraded version of the HANU-reactor featuring an integrated heat exchanger. This upgrade ensures highly efficient energy transfer in the range of -20°C to +80°C. The unit comes with an insulating, chemically resistant PTFE housing and allows superior process thermoregulation.