Application Notes

Application Notes

In order to demonstrate the unique capabilities of the HANU™ Flow Reactor, several application have been published.

Our application notes:

Application Note 3: The use of the HANU™ reactor in combination with non-invasive inline Raman spectroscopy as a tool for a real-time kinetic study of a Diels-Alder reaction

The Diels-Alder reaction between α-terpinene and maleic anhydride was performed in the HANU™ reactor in order to determine the reaction kinetics through the process window via Raman spectroscopy.

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Application Note 2: Photoinitiated thiol-ene coupling in flow

The photoinitiated thiol-ene reaction between benzyl mercaptan and 1-decene yields 46 kg sulfide per day when performed in the HANU-reactor.

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Application Note 1: Synthesis of Cookson’s diketone via intramolecular [2+2] photocycloaddition

The intramolecular [2+2]-photocycloaddition leading to Cookson’s diketone 2 was performed in the HANU-reactor with a productivity of 2.3 kg/d.

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